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ESCDL-1, a new cell line derived from chicken embryonic stem cells, supports efficient replication of Mardiviruses

13 Apr 2017

Abstract excerpt

Marek's disease virus is the etiological agent of a major lymphoproliferative disorder in poultry and the prototype of the Mardivirus genus. Primary avian somatic cells are currently used for virus replication and vaccine production, but they are largely refractory to any genetic modification compatible with the preservation of intact viral susceptibility. We explored the concept of induction of viral replication...

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PMID: 28406989
DOI: 10.1371/journal.pone.0175259

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