Epstein-Barr virus nuclear protein 2 transactivation of the latent membrane protein 1 promoter is mediated by J kappa and PU.1.

doi:10.1128/JVI.69.1.253-262.1995

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Article

Epstein-Barr virus nuclear protein 2 transactivation of the latent membrane protein 1 promoter is mediated by J kappa and PU.1.

Journal of virology - 1 Jan 1995

Johannsen E, Koh E, Mosialos G, Tong X, Kieff E, Grossman S R

Abstract excerpt

Expression of the Epstein-Barr virus (EBV) latent membrane protein 1 (LMP-1) oncogene is regulated by the EBV nuclear protein 2 (EBNA-2) transactivator. EBNA-2 is known to interact with the cellular DNA-binding protein J kappa and is recruited to promoters containing the GTGGGAA J kappa recogniti...

Topics

Antigens, Viral
Base Sequence
Cell Line
Core Binding Factor Alpha 2 Subunit
DNA Primers
DNA-Binding Proteins
Epithelial Cells
Epithelium
Epstein-Barr Virus Nuclear Antigens
Glutathione Transferase
HeLa Cells
Humans
Immunoglobulin J Recombination Signal Sequence-Binding Protein
Lymphocytes

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Identifiers

PMID: 7983717
DOI: 10.1128/JVI.69.1.253-262.1995
PMCID: PMC188571

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7983717-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Molecular Sequence Data

Mutation

Neoplasm Proteins

Nuclear Proteins