Article
Epstein-Barr virus nuclear protein 2 mutations define essential domains for transformation and transactivation.
Journal of virology - 1 May 1991
Cohen J I, Wang F, Kieff E
Abstract excerpt
Epstein-Barr virus (EBV) nuclear protein 2 (EBNA-2) is essential for B-lymphocyte growth transformation. EBNA-2 transactivates expression of the EBV latent membrane protein (LMP-1) and also transactivates expression of the B-lymphocyte proteins CD21 and CD23. In order to analyze the functional do...
Topics
- Amino Acid Sequence
- Antigens, Differentiation, B-Lymphocyte
- Antigens, Viral
- B-Lymphocytes
- Base Sequence
- Cell Transformation, Viral
- DNA, Viral
- Epstein-Barr Virus Nuclear Antigens
- Fluorescent Antibody Technique
- Herpesvirus 4, Human
- Humans
- Immunoblotting
- Molecular Sequence Data
- Mutation
- Receptors, Complement
- Receptors, Complement 3d
- Receptors, Fc
- Receptors, IgE