Article
Pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy.
Journal of virology - 1 Jan 1995
Nájera I, Holguín A, Quiñones-Mateu M E, Muñoz-Fernández M A, Nájera R, López-Galíndez C, Domingo E
Abstract excerpt
The nucleotide sequences of two pol gene regions (codons 41 to 108 and 181 to 219 of reverse transcriptase) of 60 human immunodeficiency virus type 1 genomes obtained directly from primary lymphocytes from infected individuals are reported. In addition, the mutant spectra of several quasispecies...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cells, Cultured
- Cricetinae
- DNA Primers
- DNA, Viral
- Drug Resistance, Microbial
- Genes, pol
- HIV Infections
- HIV-1
- Humans
- Molecular Sequence Data
- Mutation
- Species Specificity