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Article

Pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy.

Journal of virology - 1 Jan 1995

Nájera I, Holguín A, Quiñones-Mateu M E, Muñoz-Fernández M A, Nájera R, López-Galíndez C, Domingo E

Abstract excerpt

The nucleotide sequences of two pol gene regions (codons 41 to 108 and 181 to 219 of reverse transcriptase) of 60 human immunodeficiency virus type 1 genomes obtained directly from primary lymphocytes from infected individuals are reported. In addition, the mutant spectra of several quasispecies have been sampled by repetitive sequencing of molecular clones representing the same pol genomic regions. Average...

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Identifiers

PMID: 7983713
DOI: 10.1128/JVI.69.1.23-31.1995
PMCID: PMC188544

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