Article
Emergence of drug resistance mutations in human immunodeficiency virus type 2-infected subjects undergoing antiretroviral therapy.
Journal of clinical microbiology - 1 Apr 2000
Rodés B, Holguín A, Soriano V, Dourana M, Mansinho K, Antunes F, González-Lahoz J
Abstract excerpt
The reverse transcriptase (RT) and protease genes from 12 human immunodeficiency virus type 2 (HIV-2)-infected individuals who had been exposed to antiretroviral drugs for longer than 6 months were examined for the presence of mutations which could be involved in drug resistance. Four individuals carried virus genotypes with amino acid substitutions potentially associated with resistance to nucleoside analogues:...
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