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Article

Analysis of polymorphic variation in drug metabolism: III. Glucuronidation and sulfation of diflunisal in man.

Clinical and investigative medicine. Medecine clinique et experimentale - 1 Aug 1994

Herman R J, Loewen G R, Antosh D M, Taillon M R, Hussein S, Verbeeck R K

Abstract excerpt

The urinary excretion of diflunisal (D) and its metabolites diflunisal sulfate (DS), diflunisal phenolic glucuronide (DPG), and diflunisal acyl glucuronide (DAG) were measured in 110 healthy, drug-free Caucasian volunteers given 50 mg of diflunisal by mouth. When expressed as fractional recoverie...

Topics

Adolescent
Adult
Aged
Contraceptives, Oral
Diflunisal
Female
Genetic Variation
Glucuronates
Humans
Male
Middle Aged
Pharmaceutical Preparations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Regression Analysis

Smoking

Statistics as Topic

Sulfates

Source

Identifiers

PMID: 7982293

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7982293-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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