Article
Androgen sulfation in healthy UDP-glucuronosyl transferase 2B17 enzyme-deficient men.
The Journal of clinical endocrinology and metabolism - 1 Nov 2011
Schulze Jenny J, Thörngren John-Olof, Garle Mats, Ekström Lena, Rane Anders
Abstract excerpt
CONTEXT: The conspicuous interindividual differences in metabolism and urinary excretion of testosterone and its metabolites make it challenging to reveal testosterone doping. The variation in testosterone glucuronide excretion is strongly associated with a deletion polymorphism in the uridine diphosphate-glucuronosyltranferase (UGT) 2B17 gene. OBJECTIVE: The objective of the study was to identify additional...
Topics
- Adolescent
- Adult
- Alleles
- Androgens
- Doping in Sports
- Gene Frequency
- Glucuronosyltransferase
- Humans
- Male
- Middle Aged
- Minor Histocompatibility Antigens
- Testosterone
