Article
Xid -associated resistance to experimental Chagas' disease is IFN-gamma dependent.
1 Oct 1993
Abstract excerpt
In contrast to normal Balb/c, Balb.Xid immunodeficient mice are naturally resistant to Trypanosoma cruzi infection. Thus, Balb.Xid mice control parasitemia, do not show the characteristic wasting in the acute infection and develop no tissue pathology in the skeletal or cardiac muscles in the chronic phase of disease. By in situ hybridization and semiquantitative polymerase chain reaction, the expression of IL...
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