Hepatitis C virus quasispecies in the natural course of HCV-related disease in patients with haemophilia.

doi:10.1046/j.1365-2516.2003.00846.x

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Article

Hepatitis C virus quasispecies in the natural course of HCV-related disease in patients with haemophilia.

Haemophilia : the official journal of the World Federation of Hemophilia - 1 Jan 2004

Tagariello G, Gerotto M, Pontisso P, Belvini D, Salviato R, Radossi P, Alberti A

Abstract excerpt

Patients with haemophilia show high prevalence of hepatitis C infection but low rate of progressive liver disease when they are not co-infected with HIV. The balance between host immune system and hepatitis C virus (HCV) variability seems to play a major role in the evolution of the HCV-related disease. To address this point we have studied, in a group of selected patients with haemophilia, the composition and in...

Topics

Adult
Genotype
Hemophilia A
Hepacivirus
Hepatitis C
Heteroduplex Analysis
Humans
Male
Middle Aged
Polymerase Chain Reaction
RNA, Viral

Source

Open in PubMed

Identifiers

PMID: 14962225
DOI: 10.1046/j.1365-2516.2003.00846.x

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