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Article

Structural features of adenovirus 2 virus-associated RNA required for binding to the protein kinase DAI.

Nucleic acids research - 25 Oct 1994

Clarke P A, Pe'ery T, Ma Y, Mathews M B

Abstract excerpt

The double-stranded RNA activated protein kinase DAI contains an RNA binding domain consisting of two copies of a double-stranded RNA binding motif. We have investigated the role of RNA structure in the interaction between DAI and the structured single-stranded RNA, adenovirus VA RNAI, which inhibits DAI activation. Mutations in the apical stem, terminal stem, and central domain of the RNA were tested to assess...

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Identifiers

PMID: 7971266
DOI: 10.1093/nar/22.21.4364
PMCID: PMC308468

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Structural features of adenovirus 2 virus-associated RNA required for binding to the protein kinase DAI.PMID 7971266Read ↗

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