Article
Structural features of adenovirus 2 virus-associated RNA required for binding to the protein kinase DAI.
Nucleic acids research - 25 Oct 1994
Clarke P A, Pe'ery T, Ma Y, Mathews M B
Abstract excerpt
The double-stranded RNA activated protein kinase DAI contains an RNA binding domain consisting of two copies of a double-stranded RNA binding motif. We have investigated the role of RNA structure in the interaction between DAI and the structured single-stranded RNA, adenovirus VA RNAI, which inhi...
Topics
- Adenoviruses, Human
- Base Sequence
- Binding Sites
- Electrochemistry
- Enzyme Activation
- Escherichia coli
- Gene Deletion
- Humans
- Molecular Sequence Data
- Mutagenesis
- Mutation
- Nucleic Acid Conformation