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Article

Structural and functional analyses of stem-loop 1 of the Sindbis virus genome.

Virology - 5 Jan 2008

Nickens David G, Hardy Richard W

Abstract excerpt

Alphavirus genome function is controlled by elements at both the 5' and 3' ends. The 5' 220 nt of the Sindbis virus genome is predicted to consist of four stem-loop structures the first of which has been demonstrated to be required for efficient minus-strand RNA synthesis. To understand the role of the structure of the first stem-loop (SL1) in regulating genome function, we performed enzymatic and chemical...

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Identifiers

PMID: 17900652
DOI: 10.1016/j.virol.2007.08.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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