Use of electrophoretic mobility to determine the secondary structure of a small antisense RNA.

doi:10.1093/nar/19.11.2971

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Article

Use of electrophoretic mobility to determine the secondary structure of a small antisense RNA.

Nucleic acids research - 11 Jun 1991

Jacques J P, Susskind M M

Abstract excerpt

Natural antisense RNAs have stem-loop (hairpin) secondary structures that are important for their function. The sar antisense RNA of phage P22 is unusual: the 3' half of the molecule forms an extensive stem-loop, but potential structures for the 5' half are not predicted to be thermodynamically s...

Topics

Base Sequence
Electrophoresis, Polyacrylamide Gel
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Plasmids
RNA, Antisense
Transcription, Genetic

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