Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative analysis of the structure and function of adenovirus virus-associated RNAs

1 Nov 1993

Abstract excerpt

The protein kinase DAI is an important component of the interferon-induced cellular defense mechanism. In cells infected by adenovirus type 2 (Ad2), activation of the kinase is prevented by the synthesis of a small, highly ordered virus-associated (VA) RNA, VA RNAI. The inhibitory function of this RNA depends on its structure, which has been partially elucidated by a combination of mutagenesis and RNase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA Interference and Gene Delivery
Share to Viral Infections and Immunology Research
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8411363
DOI: 10.1128/jvi.67.11.6605-6617.1993

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative analysis of the structure and function of adenovirus virus-associated RNAsPMID 8411363Read ↗

Structure, function, and evolution of adenovirus-associated RNA: a phylogenetic approachSemantic proximity Read ↗

Structural features of adenovirus 2 virus-associated RNA required for binding to the protein kinase DAI.Semantic proximity Read ↗

Secondary and tertiary structure in the central domain of adenovirus type 2 VA RNA I.Semantic proximity Read ↗

Interaction of adenovirus VA RNAl with the protein kinase DAI: nonequivalence of binding and function.Semantic proximity Read ↗

Systematic deletion of the adenovirus-associated RNAI terminal stem reveals a surprisingly active RNA inhibitor of double-stranded RNA-activated protein kinase.Semantic proximity Read ↗

In vitro analysis of virus-associated RNA I (VAI RNA): inhibition of the double-stranded RNA-activated protein kinase PKR by VAI RNA mutants correlates with the in vivo phenotype and the structural integrity of the central domain.Semantic proximity Read ↗

Adenovirus VA RNA: An essential pro-viral non-coding RNASemantic proximity Read ↗

Impact of the structural integrity of the three-way junction of adenovirus VAI RNA on PKR inhibition.Semantic proximity Read ↗

Suppression of RNA interference by adenovirus virus-associated RNA.Semantic proximity Read ↗

Adenovirus virus-associated RNA and translation controlSemantic proximity Read ↗

The 5'-end heterogeneity of adenovirus virus-associated RNAI contributes to the asymmetric guide strand incorporation into the RNA-induced silencing complex.Semantic proximity Read ↗

The adenovirus VA RNA-derived miRNAs are not essential for lytic virus growth in tissue culture cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.