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Article

Proton motive force-driven and ATP-dependent drug extrusion systems in multidrug-resistant Lactococcus lactis.

Journal of bacteriology - 1 Nov 1994

Bolhuis H, Molenaar D, Poelarends G, van Veen H W, Poolman B, Driessen A J, Konings W N

Abstract excerpt

Three mutants of Lactococcus lactis subsp. lactis MG1363, termed EthR, DauR, and RhoR, were selected for resistance to high concentrations of ethidium bromide, daunomycin, and rhodamine 6G, respectively. These mutants were found to be cross resistant to a number of structurally and functionally unrelated drugs, among which were typical substrates of the mammalian multidrug transporter (P-glycoprotein) such as...

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Identifiers

PMID: 7961458
DOI: 10.1128/jb.176.22.6957-6964.1994
PMCID: PMC197067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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