Article
Proton motive force-driven and ATP-dependent drug extrusion systems in multidrug-resistant Lactococcus lactis.
Journal of bacteriology - 1 Nov 1994
Bolhuis H, Molenaar D, Poelarends G, van Veen H W, Poolman B, Driessen A J, Konings W N
Abstract excerpt
Three mutants of Lactococcus lactis subsp. lactis MG1363, termed EthR, DauR, and RhoR, were selected for resistance to high concentrations of ethidium bromide, daunomycin, and rhodamine 6G, respectively. These mutants were found to be cross resistant to a number of structurally and functionally u...
Topics
- Adenosine Triphosphate
- Biological Transport
- Daunorubicin
- Dose-Response Relationship, Drug
- Drug Resistance, Microbial
- Drug Resistance, Multiple
- Ethidium
- Lactococcus lactis
- Membrane Potentials
- Mutation
- Nigericin
- Protons
- Valinomycin
- Vancomycin