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Article

Drug extrusion in Corynebacterium glutamicum.

Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 1997

Kaidoh K, Kimura M, Miyauchi S, Nara T, Kamo N

Abstract excerpt

We selected a mutant of Corynebacterium glutamicum, EBR, which can grow in a medium containing cytotoxic ethidium bromide (EtBr) at a high concentration of 100 microM. The resistance to EtBr in the mutant was reversed by 2 microM reserpine, a potent inhibitor of mammalian p-glycoprotein and bacterial multidrug resistance (MDR) transporter, whereas reserpine alone had a minimal effect on cell growth. The mutant...

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Identifiers

PMID: 9442486
DOI: 10.1089/mdr.1997.3.345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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