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Article

EmrE, a small Escherichia coli multidrug transporter, protects Saccharomyces cerevisiae from toxins by sequestration in the vacuole.

Journal of bacteriology - 1 Feb 1999

Yelin R, Rotem D, Schuldiner S

Abstract excerpt

In this report we describe the functional expression of EmrE, a 110-amino-acid multidrug transporter from Escherichia coli, in the yeast Saccharomyces cerevisiae. To allow for phenotypic complementation, a mutant strain sensitive to a series of cationic lipophilic drugs was first identified. A hemagglutinin epitope-tagged version of EmrE (HA-EmrE) conferring resistance to a wide variety of drugs, including...

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Identifiers

PMID: 9922260
DOI: 10.1128/JB.181.3.949-956.1999
PMCID: PMC93463

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EmrE, a small Escherichia coli multidrug transporter, protects Saccharomyces cerevisiae from toxins by sequestration in the vacuole.PMID 9922260Read ↗

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