Bacterial multidrug resistance is due to a single membrane protein which functions as a drug pump.

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Article

Bacterial multidrug resistance is due to a single membrane protein which functions as a drug pump.

The Journal of biological chemistry - 25 Nov 1994

Grinius L L, Goldberg E B

Abstract excerpt

Multidrug transport system in proteoliposomes was reconstituted using the highly purified membrane transport protein responsible for bacterial multidrug resistance. This protein (named Smr, for staphylococcal multidrug resistance) consists of 107 amino acid residues and displays four putative tra...

Topics

Amino Acid Sequence
Antiporters
Aspartic Acid
Bacterial Proteins
Base Sequence
Carrier Proteins
DNA Mutational Analysis
DNA Primers
Drug Resistance, Microbial
Drug Resistance, Multiple
Escherichia coli Proteins
Glutamic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hydrogen-Ion Concentration

Membrane Proteins

Molecular Sequence Data

Phenotype

Proteolipids

Staphylococcus

Source

Open in PubMed

Identifiers

PMID: 7962000

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7962000-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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