Article
Bacterial multidrug resistance is due to a single membrane protein which functions as a drug pump.
The Journal of biological chemistry - 25 Nov 1994
Grinius L L, Goldberg E B
Abstract excerpt
Multidrug transport system in proteoliposomes was reconstituted using the highly purified membrane transport protein responsible for bacterial multidrug resistance. This protein (named Smr, for staphylococcal multidrug resistance) consists of 107 amino acid residues and displays four putative transmembrane domains. The Smr protein was tagged with a FLAG epitope, and the modified protein was expressed, purified,...
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