Article
Evidence of active efflux in resistance to ciprofloxacin and to ethidium bromide by Mycoplasma hominis.
Antimicrobial agents and chemotherapy - 1 Mar 2002
Raherison S, Gonzalez P, Renaudin H, Charron A, Bébéar C, Bébéar C M
Abstract excerpt
The uptake of fluoroquinolones was characterized for the fluoroquinolone-susceptible strain PG21 of Mycoplasma hominis. Accumulation of fluoroquinolones appeared to occur by passive diffusion. Addition of arginine as the energizer significantly reduced the uptake of fluoroquinolones, suggesting the presence of an energy-dependent efflux process. Reserpine and orthovanadate, two multidrug pump inhibitors,...
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