Yeast prt1 mutations alter heat-shock gene expression through transcript fragmentation.

doi:10.1002/j.1460-2075.1993.tb06002.x

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Article

Yeast prt1 mutations alter heat-shock gene expression through transcript fragmentation.

The EMBO journal - 1 Aug 1993

Barnes C A, Singer R A, Johnston G C

Abstract excerpt

The inhibition of translation initiation by modification or mutation of initiation factors can lead to disproportionate effects on gene expression. Here we report disproportionate decreases in gene expression in cells with mutated Prt1 activity. The PRT1 gene product of the budding yeast Saccharo...

Topics

Alleles
Eukaryotic Initiation Factor-3
Fungal Proteins
Gene Expression
Genes, Fungal
Heat-Shock Proteins
Hot Temperature
Mutation
RNA, Fungal
RNA, Messenger
Recombinant Fusion Proteins
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

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