Article
Caenorhabditis elegans unc-51 gene required for axonal elongation encodes a novel serine/threonine kinase.
Genes & development - 15 Oct 1994
Ogura K, Wicky C, Magnenat L, Tobler H, Mori I, Müller F, Ohshima Y
Abstract excerpt
Mutations in the unc-51 gene of the nematode Caenorhabditis elegans result in various abnormalities in axonal elongation and axonal structures. We cloned the unc-51 gene by tagging with the transposon Tc1. The wild-type unc-51 gene, which rescued the mutant phenotypes, encodes a novel serine/thre...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Axons
- Base Sequence
- Caenorhabditis elegans
- Cloning, Molecular
- DNA Transposable Elements
- DNA, Complementary
- DNA, Helminth
- Female
- Gene Expression Regulation, Developmental
- Genes, Helminth
- Molecular Sequence Data
- Nerve Net
- Point Mutation
- Protein Serine-Threonine Kinases
- Sequence Homology, Amino Acid