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Article

Molecular and genetic analysis of unc-7, a Caenorhabditis elegans gene required for coordinated locomotion.

Genetics - 1 Mar 1993

Starich T A, Herman R K, Shaw J E

Abstract excerpt

Mutations in the Caenorhabditis elegans gene unc-7 confer an uncoordinated phenotype. Wild-type animals trace smooth, sinuous waves as they move; unc-7 mutants make irregular bends or kinks along their bodies, particularly when they move forward. The unc-7 locus has also been implicated in the nematode's response to volatile anesthetics. We have cloned unc-7 by transposon tagging: an unc-7 mutation was correlated...

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Identifiers

PMID: 7681023
DOI: 10.1093/genetics/133.3.527
PMCID: PMC1205341

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