Molecular and genetic analysis of unc-7, a Caenorhabditis elegans gene required for coordinated locomotion.

doi:10.1093/genetics/133.3.527

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Article

Molecular and genetic analysis of unc-7, a Caenorhabditis elegans gene required for coordinated locomotion.

Genetics - 1 Mar 1993

Starich T A, Herman R K, Shaw J E

Abstract excerpt

Mutations in the Caenorhabditis elegans gene unc-7 confer an uncoordinated phenotype. Wild-type animals trace smooth, sinuous waves as they move; unc-7 mutants make irregular bends or kinks along their bodies, particularly when they move forward. The unc-7 locus has also been implicated in the nematode's response to volatile anesthetics. We have cloned unc-7 by transposon tagging: an unc-7 mutation was correlated...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Chromosome Mapping
Cloning, Molecular
DNA
DNA Mutational Analysis
DNA Transposable Elements

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Rearrangement

Genes, Helminth

Helminth Proteins

Ion Channels

Locomotion

Membrane Proteins

Molecular Sequence Data

Source

Open in PubMed Open full text

Identifiers

PMID: 7681023
DOI: 10.1093/genetics/133.3.527
PMCID: PMC1205341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7681023-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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