Article
The C. elegans unc-104 gene encodes a putative kinesin heavy chain-like protein.
Neuron - 1 Jan 1991
Otsuka A J, Jeyaprakash A, García-Añoveros J, Tang L Z, Fisk G, Hartshorne T, Franco R, Born T
Abstract excerpt
Mutations in the unc-104 gene of the nematode C. elegans result in uncoordinated and slow movement. Transposon insertions in three unc-104 alleles (e2184, rh1016, and rh1017) were used as physical markers to clone the unc-104 gene. DNA sequence analysis of unc-104 cDNAs revealed an open reading frame capable of encoding a 1584 amino acid protein with similarities to kinesin heavy chain. The similarities are...
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