The C. elegans unc-104 gene encodes a putative kinesin heavy chain-like protein.

doi:10.1016/0896-6273(91)90126-k

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Article

The C. elegans unc-104 gene encodes a putative kinesin heavy chain-like protein.

Neuron - 1 Jan 1991

Otsuka A J, Jeyaprakash A, García-Añoveros J, Tang L Z, Fisk G, Hartshorne T, Franco R, Born T

Abstract excerpt

Mutations in the unc-104 gene of the nematode C. elegans result in uncoordinated and slow movement. Transposon insertions in three unc-104 alleles (e2184, rh1016, and rh1017) were used as physical markers to clone the unc-104 gene. DNA sequence analysis of unc-104 cDNAs revealed an open reading frame capable of encoding a 1584 amino acid protein with similarities to kinesin heavy chain. The similarities are...

Topics

Adenosine Triphosphatases
Adenosine Triphosphate
Alleles
Amino Acid Sequence
Animals
Base Sequence
Binding Sites
Caenorhabditis
Cloning, Molecular
DNA
DNA Transposable Elements

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Deoxyribonuclease EcoRI

Kinesins

Microtubules

Molecular Sequence Data

Mutation

Restriction Mapping

Source

Open in PubMed

Identifiers

PMID: 1846075
DOI: 10.1016/0896-6273(91)90126-k

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1846075-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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