Article
TP53 - molecular soldier's mutations in bladder cancer in the Kashmiri population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011
Nanda Mahoor S, Shah Zaffar A, Sameer A Syed, Syeed Nidda, Murtaza Imtiyaz, Siddiqi Mushtaq A, Ali Arif
Abstract excerpt
PURPOSE: We made a preliminary attempt to study mutations in exons 5-8 (the DNA binding domain) of the tumor suppressor gene TP53, in urinary bladder cancer patients from Kashmir. Further the relation of clinicopathological characteristics with mutation status was asessed. MATERIALS AND METHODS: The study population consisted of 60 patients diagnosed with transitional cell carcinomas who underwent transurethral...
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