Article
Computer program for the analysis of mutational spectra: application to p53 mutations.
Carcinogenesis - 1 Oct 1994
Cariello N F, Piegorsch W W, Adams W T, Skopek T R
Abstract excerpt
Mutations in the p53 oncogene are extremely common in human cancers, and environmental exposure to mutagenic agents may play a role in the frequency and nature of the mutations. Differences in the patterns of p53 mutations have been observed for different tumor types. It is not trivial to determi...
Topics
- Base Composition
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Small Cell
- Colonic Neoplasms
- Genes, p53
- Humans
- Lung Neoplasms
- Mutation
- Neoplasms
- Smoking
- Software
- Urinary Bladder Neoplasms