Article
Germline and somatic abnormalities of chromosome 7 in Wilms' tumor.
Cancer genetics and cytogenetics - 15 Oct 1994
Wilmore H P, White G F, Howell R T, Brown K W
Abstract excerpt
Although a gene (WT1) located at chromosome 11p13 is implicated in the development of Wilms' tumor (WT), there is evidence that genes on other chromosomes are also involved. A WT patient presented with a constitutional balanced translocation between chromosomes 1 and 7, t(1;7)(q42;p15), the breakpoints of which could represent a WT predisposition gene in this patient. Cytogenetic analysis of the tumor from this...
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