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Article

Genetics of Wilms' tumor.

Seminars in urologic oncology - 1 Feb 1999

Coppes M J, Egeler R M

Abstract excerpt

The molecular genetic characterization of Wilms' tumor has played a prominent role in advancing our knowledge of the genetic aspects underlying the development of cancer in general. Unlike the genetic mechanism leading to the development of retinoblastoma, an embryonal tumor of childhood affecting the retina, which only requires the inactivation of one single gene, the biological pathways leading to the...

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PMID: 10073400

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