Identification of a new WT1 mutation in a sporadic Wilms' tumour.

doi:10.1016/s0925-4439(98)00032-5

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Article

Identification of a new WT1 mutation in a sporadic Wilms' tumour.

Biochimica et biophysica acta - 14 Aug 1998

Santos A C, Boavida M G, Costa A, Osorio-Almeida L

Abstract excerpt

A new mutation in WT1 is described in a sporadic unilateral Wilms' tumour consisting of a 17 bp duplication in exon 7 generating a stop codon. The second allele is either partially deleted or presents the same alteration. LOH analysis at 11p15.5 and at the 16q13-16q24.3 regions indicated retentio...

Topics

Child, Preschool
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 16
DNA Mutational Analysis
Genes, Wilms Tumor
Humans
Loss of Heterozygosity
Male
Mutation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Repetitive Sequences, Nucleic Acid
Sequence Analysis, DNA
Wilms Tumor

Source

Open in PubMed

Identifiers

PMID: 9685601
DOI: 10.1016/s0925-4439(98)00032-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9685601-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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