Article
Axon guidance mechanisms in Caenorhabditis elegans.
Current opinion in genetics & development - 1 Aug 1994
Culotti J G
Abstract excerpt
Genetic studies have identified an extracellular path cue molecule, UNC-6, and a neuronal receptor, UNC-5, that act to guide migrating pioneer growth cones along the dorsoventral coordinate of the Caenorhabditis elegans body wall. Ectopic expression studies and characterization of mutants have de...
Topics
- Animals
- Axons
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Movement
- Cell Polarity
- Chemotactic Factors
- Embryo, Nonmammalian
- Gene Expression Regulation, Developmental
- Helminth Proteins
- Membrane Proteins
- Mutation
- Nerve Growth Factors
- Nerve Tissue Proteins
- Netrins
- Neural Pathways
- Receptors, Cell Surface
- Receptors, Growth Factor
