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Article

Neurons refine the Caenorhabditis elegans body plan by directing axial patterning by Wnts.

PLoS biology - 1 Jan 2013

Modzelewska Katarzyna, Lauritzen Amara, Hasenoeder Stefan, Brown Louise, Georgiou John, Moghal Nadeem

Abstract excerpt

Metazoans display remarkable conservation of gene families, including growth factors, yet somehow these genes are used in different ways to generate tremendous morphological diversity. While variations in the magnitude and spatio-temporal aspects of signaling by a growth factor can generate different body patterns, how these signaling variations are organized and coordinated during development is unclear. Basic...

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PMID: 23319891
DOI: 10.1371/journal.pbio.1001465
PMCID: PMC3539944

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