Article
UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans.
Neuron - 1 Nov 1992
Ishii N, Wadsworth W G, Stern B D, Culotti J G, Hedgecock E M
Abstract excerpt
The unc-6 gene is required for the guidance of pioneer axons and migrating cells along the body wall in C. elegans. In mutants, dorsal and ventral migrations are disrupted, but longitudinal movements are largely unaffected. The gene was tagged for molecular cloning by two independent transposon i...
Topics
- Amino Acid Sequence
- Animals
- Axons
- Base Sequence
- Blotting, Southern
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Movement
- Cloning, Molecular
- DNA
- DNA Transposable Elements
- Exons
- Helminth Proteins
- Laminin
- Molecular Sequence Data
- Mutation
- Nerve Tissue Proteins
- Netrins