Article
The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans.
Neuron - 1 Jan 1990
Hedgecock E M, Culotti J G, Hall D H
Abstract excerpt
Three known genes guide circumferential migrations of pioneer axons and mesodermal cells on the nematode body wall. unc-5 affects dorsal migrations, unc-40 primarily affects ventral migrations, and unc-6 affects migrations in both directions. Circumferential movements still occur, but are misdirected whereas longitudinal movements are normal in these mutants. Pioneer growth cones migrating directly on the...
Topics
- Animals
- Axons
- Cell Division
- Cell Movement
- Epidermal Cells
- Genes
- Muscles
- Nematoda
- Nervous System
- Phenotype