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Article

Suppressors of ectopic UNC-5 growth cone steering identify eight genes involved in axon guidance in Caenorhabditis elegans.

Developmental biology - 1 Feb 1998

Colavita A, Culotti J G

Abstract excerpt

The UNC-5 guidance receptor, in response to the UNC-6/netrin path cue, orients growing axons in a dorsal direction along the epidermis of Caenorhabditis elegans. When ectopically expressed in the touch neurons, which normally extend ventrally or longitudinally, UNC-5 is able to reorient their axo...

Topics

Animals
Ankyrins
Axons
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cytoskeleton
Genes, Helminth
Helminth Proteins
Membrane Proteins
Mutation
Receptors, Cell Surface
Receptors, Growth Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9473333
DOI: 10.1006/dbio.1997.8790

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9473333-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Suppressors of ectopic UNC-5 growth cone steering identify eight genes involved in axon guidance in Caenorhabditis elegans.PMID 9473333Read ↗

Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally.Semantic proximity Read ↗

ENU-3 functions in an UNC-6/netrin dependent pathway parallel to UNC-40/DCC/frazzled for outgrowth and guidance of the touch receptor neurons in C. elegans.Semantic proximity Read ↗

Axon guidance mechanisms in Caenorhabditis elegans.Semantic proximity Read ↗

UNC-6/netrin and its receptors UNC-5 and UNC-40/DCC modulate growth cone protrusion in vivo in C. elegans.Semantic proximity Read ↗

Genetic analysis of growth cone migrations in Caenorhabditis elegans.Semantic proximity Read ↗

Extracellular matrix regulates UNC-6 (netrin) axon guidance by controlling the direction of intracellular UNC-40 (DCC) outgrowth activity.Semantic proximity Read ↗

ENU-3 is a novel motor axon outgrowth and guidance protein in C. elegans.Semantic proximity Read ↗

Genes that guide growth cones along the C. elegans ventral nerve cord.Semantic proximity Read ↗

Shared receptors in axon guidance: SAX-3/Robo signals via UNC-34/Enabled and a Netrin-independent UNC-40/DCC function.Semantic proximity Read ↗

UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans.Semantic proximity Read ↗

The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans.Semantic proximity Read ↗

Identification of domains of netrin UNC-6 that mediate attractive and repulsive guidance and responses from cells and growth cones.Semantic proximity Read ↗

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