The role of p53 in tumor progression.

Abstract excerpt

p53 mutation is a common event in tumors. The evidence that such mutation is an important step in the sequence of genetic changes which underly tumor progression is outlined. Such evidence includes the study of human tumors, animal tumor models and cell culture. In several instances, p53 mutation seems to be a late event. This is by no means a universal finding, and important reservations are stated concerning...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Liver Neoplasms
• Share to Mutation
• Share to Neoplasms