Article
The role of p53 in tumor progression.
Seminars in cancer biology - 1 Jun 1994
Blondal J A, Benchimol S
Abstract excerpt
p53 mutation is a common event in tumors. The evidence that such mutation is an important step in the sequence of genetic changes which underly tumor progression is outlined. Such evidence includes the study of human tumors, animal tumor models and cell culture. In several instances, p53 mutation...
Topics
- Animals
- Colorectal Neoplasms
- Female
- Genes, p53
- Humans
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Liver Neoplasms
- Mutation
- Neoplasms
- Uterine Cervical Neoplasms