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Article

Hypermutability in carcinogenesis.

Genetics - 1 Apr 1998

Strauss B S

Abstract excerpt

The presence of numerous chromosomal changes and point mutations in tumors is well established. At least some of these changes play a role in the development of the tumors. It has been suggested that the number of these genetic changes requires that tumorigenesis involves an increase in mutation rate. However, the presence of numerous changes can also be accounted for by efficient selection. What is required to...

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Identifiers

PMID: 9560381
DOI: 10.1093/genetics/148.4.1619
PMCID: PMC1460074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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