Article
Rapid detection of -alpha 4.2 deletion of alpha-thalassemia-2 by polymerase chain reaction.
Annals of hematology - 1 Oct 1994
Chang J G, Liu T C, Chiou S S, Chen J T, Chen T P, Lin C P
Abstract excerpt
We sequenced part of the X boxes of alpha-thalassemia-1 of Southeast Asia type (- -SEA) with -alpha 4.2, -alpha 3.7, -alpha G-Taichung, and alpha CS alpha. We found the X box of -alpha 3.7 belonged to the X box of alpha 2 globin gene and the X box of alpha CS alpha contained X boxes of both alpha 1 and alpha 2 globin gene, whereas the X box of -alpha 4.2 and -alpha G-Taichung was a hybrid of X boxes of alpha 2...
Topics
- Base Sequence
- DNA
- Gene Deletion
- Globins
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- alpha-Thalassemia