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Article

Detection of common deletional alpha-thalassemia-2 determinants by PCR.

American journal of hematology - 1 Jul 1994

Baysal E, Huisman T H

Abstract excerpt

We have developed a rapid approach to detect the two most common alpha-thalassemia-2 (alpha-thal-2) determinants by the polymerase chain reaction (PCR) technique, which takes a few hours to complete. Specific oligonucleotides selectively amplify appropriate segments of the chromosome with the deletion and the normal chromosome under identical experimental conditions, and the products are identified by...

Topics

Base Sequence
Child
Gene Deletion
Genotype
Globins
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Restriction Mapping
alpha-Thalassemia

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8192150
DOI: 10.1002/ajh.2830460309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8192150-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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