Detection of beta-thalassemia mutations in the Chinese using amplified DNA from dried blood specimens.

doi:10.1007/BF00208926

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Article

Detection of beta-thalassemia mutations in the Chinese using amplified DNA from dried blood specimens.

Human genetics - 1 Jan 1990

Huang S Z, Zhou X D, Zhu H, Ren Z R, Zeng Y T

Abstract excerpt

This paper describes DNA polymerase chain reaction (PCR) amplification directly from dried blood specimens for the detection of the beta-thalassemia mutation in China. Target DNA was amplified to span the beta-globin gene regions, which included ten types of mutation sites specific for Chinese be...

Topics

Base Sequence
China
Gene Amplification
Gene Frequency
Globins
Humans
Molecular Sequence Data
Mutation
Oligonucleotide Probes
Polymerase Chain Reaction
Thalassemia

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