Article
Molecular characterization of Hb H disease by polymerase chain reaction.
Acta haematologica - 1 Jan 1993
Chen T P, Lin S F, Chang J G, Tsao C J, Liu T C, Chiou S S, Liu H W
Abstract excerpt
We utilized the PCR method to amplify the alpha-thalassemia-1 breakpoint area of the Southeast Asia type and several regions of the alpha-globin gene cluster to diagnose rightward deletion (-alpha 3.7), leftward deletion (-alpha 4.2) or nondeletion forms of the Hb H disease. For the nondeletion f...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Base Sequence
- Child
- Child, Preschool
- DNA Primers
- Gene Deletion
- Hemoglobin H
- Humans
- Middle Aged
- Molecular Sequence Data
- Polymerase Chain Reaction
- Taiwan
- alpha-Thalassemia