Article
Study of beta-Thalassemia mutations using the polymerase chain reaction-amplification refractory mutation system and direct DNA sequencing techniques in a group of Egyptian Thalassemia patients.
Hemoglobin - 1 Jan 2007
El-Gawhary Somaia, El-Shafie Shahira, Niazi Manal, Aziz Mona, El-Beshlawy Amal
Abstract excerpt
The aim of this study was the molecular characterization of beta-thalassemia (thal) mutations in a group of 95 Egyptian thalassemic patients from Fayoum in Upper Egypt, Cairo, Alexandria and Tanta in Lower Egypt and the Nile Delta. To identify these anomalies, the polymerase chain reaction-amplif...
Topics
- Amino Acid Sequence
- Base Sequence
- Child
- Child, Preschool
- Consanguinity
- DNA Mutational Analysis
- Egypt
- Female
- Genetic Testing
- Genetics, Population
- Globins
- Humans