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Article

Novel technique for rapid detection of alpha-globin gene mutations and deletions.

Translational research : the journal of laboratory and clinical medicine - 1 Mar 2010

Liu Jingzhong, Jia Xingyuan, Tang Ning, Zhang Xu, Wu Xiaoyi, Cai Ren, Wang Lirong, Liu Quanzhang, Xiao Bai, Zhu Jim, Wang Qingtao

Abstract excerpt

Populations in Southeast Asia and South China have high frequencies of alpha-thalassemia caused by alpha-globin gene mutations and/or deletions. This study was designed to find an efficient and simple diagnostic test for the mutations and deletions. A duplex polymerase chain reaction (PCR)/denaturing high-pressure liquid chromatography (DHPLC) was used to detect the mutations and deletions. A blinded study of 110...

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PMID: 20171600
DOI: 10.1016/j.trsl.2009.10.003

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SEA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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