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Article

Multiple sites of action of volatile anesthetics in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 1 Apr 1990

Morgan P G, Sedensky M, Meneely P M

Abstract excerpt

The mechanism and site(s) of action of volatile anesthetics are unknown. In all organisms studied, volatile anesthetics adhere to the Meyer-Overton relationship--that is, a ln-ln plot of the oil-gas partition coefficients versus the potencies yields a straight line with a slope of -1. This relationship has led to two conclusions about the site of action of volatile anesthetics. (i) It has properties similar to...

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Identifiers

PMID: 2326259
DOI: 10.1073/pnas.87.8.2965
PMCID: PMC53814

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Multiple sites of action of volatile anesthetics in Caenorhabditis elegans.PMID 2326259Read ↗

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