A conserved AUG triplet in the 5' nontranslated region of poliovirus can function as an initiation codon in vitro and in vivo.

doi:10.1006/viro.1994.1588

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Article

A conserved AUG triplet in the 5' nontranslated region of poliovirus can function as an initiation codon in vitro and in vivo.

Virology - 1 Nov 1994

Pestova T V, Hellen C U, Wimmer E

Abstract excerpt

Poliovirus translation is initiated at AUG743, 154 nt downstream of a conserved heptanucleotide CUUAUGG at the 3' border of the internal ribosome entry site. AUG586 is part of this motif and is normally not an initiation codon, but was activated following alteration of its context from CUUAUGG to...

Topics

Base Sequence
Codon
Conserved Sequence
HeLa Cells
Humans
Molecular Sequence Data
Phenotype
Poliovirus

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