Article
Translational efficiency of a non-AUG initiation codon is significantly affected by its sequence context in yeast.
The Journal of biological chemistry - 8 Feb 2008
Chen Shun-Jia, Lin Grace, Chang Kuang-Jung, Yeh Lu-Shu, Wang Chien-Chia
Abstract excerpt
Previous studies have shown that translation of mrna for yeast glycyl-tRNA synthetase is alternatively initiated from UUG and a downstream AUG initiation codon. Evidence presented here shows that unlike an AUG initiation codon, efficiency of this non-AUG initiation codon is significantly affected by its sequence context, in particular the nucleotides at positions -3 to -1 relative to the initiation codon. A/A/R...
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