Article

Defining the high-translational readthrough stop codon context

2024-12-21

Abstract excerpt

Translational termination is not entirely efficient and competes with elongation, which might result in translational readthrough (TR). TR occurs when a near-cognate tRNA binds to a stop codon, (mis)interpreting it as a sense codon and producing a C-terminal extension of the protein. This process is influenced by the stop codon itself and the surrounding nucleotide sequence, known as the stop codon context (SCC)....

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Literature Corpus work: 30a9e3a2-f1f4-533c-b455-65c985a98175
DOI: 10.1101/2024.12.20.629686

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