Article
Identification of a cis-acting element required for shunt-mediated translational initiation of the Sendai virus Y proteins.
Nucleic acids research - 15 Jan 2003
de Breyne Sylvain, Simonet Viviane, Pelet Thierry, Curran Joseph
Abstract excerpt
Shunting is a mechanism that permits translational initiation at internal codons positioned in proximity to a ribosome acceptor sequence. Sendai virus exploits shunting to express a series of proteins that initiate at the fourth and fifth start sites on the P/C mRNA (namely, the Y1 and Y2 proteins, respectively). Shunt-mediated initiation at these sites is codon independent. In an attempt to characterise the...
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