Article

An alternative AUG codon in segment 5 of the 2009 pandemic influenza A virus is a swine-derived virulence motif

2019-08-19

Abstract excerpt

The 2009 influenza A virus (IAV) pandemic (pdm2009) was caused by a swine H1N1 virus with several atypical genetic features. Here, we investigate the origin and significance of an upstream AUG (uAUG) codon in the 5’-untranslated region of the NP gene. Phylogeny indicated that the uAUG codon arose in the classical swine IAV lineage in the mid 20 th Century, and has become fixed in the current triple reassortant, v...

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Identifiers and source

Literature Corpus work: 83cc5c90-7290-5da9-ab30-a15e5ce4d976
DOI: 10.1101/738427

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