Article
Effect of restoration of retinoblastoma gene function on the radiosensitivity of cells of human tumor cell lines.
Radiation research - 1 Nov 1994
Tsang N M, Little J B
Abstract excerpt
To assess the role of expression of the retinoblastoma (RB) gene on the sensitivity of cells to the cytotoxic effects of ionizing radiation, we transfected a normal RB gene into cells of RB+ and RB- osteosarcoma cell lines and an RB- prostate carcinoma line and studied the radiosensitivity of the cells before and after transfection. Four transfected clones were isolated from the two RB- tumor cell lines that...
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