Article
[The retinoblastoma gene: will therapeutic use of its tumor suppressive properties be possible?].
Bulletin du cancer - 1 Aug 1993
Bignon Y J, Rio P
Abstract excerpt
The retinoblastoma is a rare childhood tumor which occurs in children, 40% of them being diagnosed in an hereditary context. The gene involved in the hereditary predisposition and in the tumoral development was isolated (RB-1) and is of the antioncogene-type. RB-1 mutations were found in many oth...
Topics
- Child
- Child, Preschool
- Gene Expression Regulation, Neoplastic
- Genes, Retinoblastoma
- Genetic Therapy
- Humans
- Infant
- Mutation
- Retinoblastoma