Article
A targeted-replacement system for identification of signals for de novo methylation in Neurospora crassa.
Molecular and cellular biology - 1 Nov 1994
Miao V P, Singer M J, Rountree M R, Selker E U
Abstract excerpt
Transformation of eukaryotic cells can be used to test potential signals for DNA methylation. This approach is not always reliable, however, because of chromosomal position effects and because integration of multiple and/or rearranged copies of transforming DNA can influence DNA methylation. We d...
Topics
- Alleles
- DNA, Fungal
- Gene Deletion
- Genes, Fungal
- Methylation
- Mutation
- Neurospora crassa
- Transformation, Genetic
