Article
DNA methylation associated with repeat-induced point mutation in Neurospora crassa.
Molecular and cellular biology - 1 Oct 1995
Singer M J, Marcotte B A, Selker E U
Abstract excerpt
Repeat-induced point mutation (RIP) is a process that efficiently detects DNA duplications prior to meiosis in Neurospora crassa and peppers them with G:C to A:T mutations. Cytosine methylation is typically associated with sequences affected by RIP, and methylated cytosines are not limited to CpG dinucleotides. We generated and characterized a collection of methylated and unmethylated amRIP alleles to investigate...
Topics
- Alleles
- Base Composition
- Base Sequence
- DNA, Fungal
- Genes, Fungal
- Glutamate Dehydrogenase (NADP+)
- Methylation
- Molecular Sequence Data
- Multigene Family
- Neurospora crassa
- Point Mutation
